Antoine Vermette scored twice and the Arizona Coyotes beat the Anaheim Ducks 4-2 on Wednesday night.

The Coyotes had beaten the Ducks twice already this season behind Max Domi, Anthony Duclair and Martin Hanzal. Domi and Duclair were at it again, combining for three points — including a goal in the third period shortly after Anaheim cut the lead to two.

Duclair has scored five of his eight goals against the Ducks this season and has combined with Domi for 11 points in three games.

Anaheim rallied the night before and twice cut Arizona’s lead to one on third-period goals by Sami Vantanen and Ryan Kesler before Vermette put it away with an empty-netter.

Michael Stone also scored and Mike Smith stopped 29 shots for the Coyotes.

The Ducks played Tuesday night at home, rallying to beat Calgary 5-3 behind Ryan Getzlaf’s team record-tying five assists and a relief appearance by goalie John Gibson.

Gibson started against Arizona with Freddie Andersen (illness) out for a second straight game and gave up a goal in the opening 5 minutes, when Stone scored from near the blue line with the help of Boyd Gordon’s screen.

The Coyotes broke through against the NHL’s best penalty-kill unit early in the second period, with Vermette swiping a rebound off the post for his first goal since last Feb. 14 against the New York Rangers.

The Ducks rallied in the third period against the Flames and quickly pulled within a goal against the Coyotes in the final period, scoring 38 seconds in when a shot by Vantanen went off Kesler and between Smith’s legs.

But Arizona’s D&D boys answered right back.

Domi, who had four points in the first two games against Anaheim this season, tracked down a puck from behind to keep it in the zone and found Duclair streaking back the other way. He used a deke to move Gibson out of position and flipped in a backhander to put the Coyotes back up by two goals.

The Ducks still kept coming, cutting the lead to one again when Vantanen flipped a shot past Smith on a power play, but fell short in their latest rally attempt.

NOTES: Coyotes captain Shane Doan did not play due to a lower-body injury. He is day to day. … Anaheim’s Cam Fowler had an assist to reach 127 for his career, passing Francois Beauchemin for second on the team’s all-time list among defensemen. … Coyotes D Zbynek Michalek played in game No. 559, passing Keith Yandle for third on the team’s career list for defensemen.